The phrase "most often manifest" is correct and usable in written English
It can be used to describe something that frequently appears or becomes evident.
Example: "The symptoms of the condition most often manifest in the early stages of the disease."
Alternatives: "most commonly appear" or "most frequently show"
They bear the future in their willful and lusty energies, and they deliver it with a reckless vortex of disorder and emotional turmoil that's most often manifested in a shuffling of the romantic cards, a change of partners that portends wider societal changes eddying outward from family life.
Hereditary predisposition to colorectal cancer most often manifests itself as familial adenomatous polyposis from mutations of APC, or hereditary nonpolyposis colorectal cancer, resulting from mutations of MSH2, MLH1, MSH6, or other genes.
This pain most often manifested as pelvic (symphysis pubis) pain or backache.
The disease most often manifests itself in late adolescence or early adulthood and often implies loss of social functioning and reduced quality of life.
Renal carcinoma metastasis to the large airways most often manifests with symptoms similar to a primary endobronichial tumour such as hemoptysis [32].
Renal lymphoma most often manifests as multiple bilateral renal masses and occasionally, nephromegaly.
While it most often manifests as pharyngeal, soft tissue or skin infections, it can rarely manifest as a respiratory infection.
Unlike the herpes simplex viruses, VZV requires transport from mucoepithelial cells in the upper respiratory tract where infection is established to skin cells where disease most often manifests.
In the other half, it most often manifests clinically as a thin homogenous vaginal discharge, a vaginal pH of more than 4.5, presence of 'clue cells', and an amine odour after addition of 10% of potassium hydroxide [ 1, 2].
