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Most often, major diagnostics companies expect that candidate markers have reached a fairly advanced stage in their development and validation before expressing serious interest in their pursuit, resulting in a 'death valley' conundrum for biomarkers that are in the initial stages of their development but that do not elicit sufficient interest to be pursued further.
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Since the spatial distribution of hydraulic conductivity is most often the major source of uncertainty, we focus on the direct sampling of hydraulic conductivity at prescribed locations of the aquifer.
However, the reasons for re-admissions are most often not major surgical complications but minor wound problems, suspicion of venous thromboembolism, and medication problems.
The question arises whether our findings of companies' priorities in drug development are in line with the most often occurring major objections or factors for approval failure.
For this analysis, we defined early stage illness as stages 0 to 2 and later stage illness development as stages 3 to 4, given that BD most often debuts as major depressive episodes (Duffy 2010).
The population structure most often indicates a major bottleneck and short time frame for change.
Gene duplications post-dating separation of the insect orders are unevenly distributed, most often appearing in major alpha 1 and minor beta 2 clades.
He watched his two children, whom he clearly loved, grow up: "You each give me more to be proud of than 'J R.' (Throw in 'The Recognitions' too)." He may even have eventually convinced some people that he never actually read the book that was most often cited as his major influence.
Most often they are for major updates to the platform.
We loved how our own coaching sessions or yoga classes transformed our lives and thus we became motivated to, most often times, make a major career shift so we could share what we love so much with the world.
In adults, impaired judgement is most often due to a major psychiatric disorder, such as schizophrenia, an affective disorder or anorexia nervosa.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com