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The most obvious pathological finding in MS brain tissue is focal demyelination, which may affect any part of the CNS (Chard and Miller, 2009).
Because destruction of the articular cartilage is the most obvious pathological lesion in the affected joints of individuals with OA, studies on the treatment of OA overlap with those on cartilage regeneration.
A potential problem underlying the failure to treat AD in humans is the assumption that senile plaques, the most obvious pathological hallmark of the disease, and especially one of the plaque components Aβ peptide represent the major driving force of the disease.
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Finally, increases in serum CK activity were frequently observed in cases of severe liver disease, with the most obvious source of CK being the pathological liver tissue itself [ 16- 18].
At higher magnifications, the distribution of pathological lesions with iTDP43 in certain cases remained difficult and the most obvious reason for this being the lower pathological load observed with this type of antibody, making the predominant layers involved difficult to distinguish.
The most obvious is security.
The most obvious is piracy.
The most obvious is competence.
The most obvious is location.
The most obvious is income.
Nestle is probably the most obvious buyer.
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