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The most notable transcript differences were from genes involved in carbohydrate metabolism.
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Most notable were transcripts in the nucleoli which were spectrally similar to RNA clusters in the cytoplasm.
Work from others has shown that one of the most notable splicing changes in DM1 is the imbalance of ATP2A1 transcript isoforms (17, 18), which is MBNL1 dependent in muscle cells (35).
The most notable result of this study is the high accumulation of the EgPG4 transcript in the base of the fruit containing the AZ prior to cell separation.
A few studies have investigated algorithms for transcript inference and quantification from RNA-Seq data, the most notable being the RGASP1 (2009) and RGASP2 (2010) competitions (Steijger et al., 2013).
Most notable was a clearly defined enrichment in proteins encoded by these transcripts that were components of the cytoskeleton (60.0%; p-value: 2.0×10−29), were involved in cytoskeletal organization (34.5%; p-value: 2.2×10−16), and were actin binding (45.5%; p-value: 4.7×10−31).
Following depletion of RPL11, significant increase in transcripts of all three targets was noted with the most notable increase (16.2-fold) seen for p21.
Indeed, we only identified a few instances of species-specific chemoreceptor expression; the most notable occurrences were Or33 in An. quadriannulatus and Ir7s in An. gambiae which both displayed transcript abundance levels above the median level for all transcripts.
The most notable features of the tissue expression profiles were that LcUCP1 exhibited strongest expression in the root in which transcript levels were some 100-fold greater than those detected in the other tissues.
However, early in familiarizing ourselves with the transcripts, developing the analysis codebook, and in performing preliminary analysis, it became apparent that the most notable analytical difference was stylistic rather than content-related.
The most notable event?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com