Sentence examples for most normal somatic from inspiring English sources

Telomerase is expressed in almost all cancer cells but is inactive in most normal somatic cells.

Telomerase is not expressed in most normal somatic cells but retains moderate activity in proliferative stem cells and to a higher extent in male germ line cells.

In contrast, higher vertebrates have more tightly regulated telomerase activity and most normal somatic cells usually do not have active telomerase, except for stem/progenitor cells.

In most normal somatic cells, telomerase is repressed and telomeres progressively shorten, leading to limited proliferative lifespan [ 2, 56].

Most normal somatic cells lack telomerase activity, whereas telomerase activation is observed in proliferating cells and cancer cells [ 3, 4].

In humans, most normal somatic cells do not express telomerase, the enzyme capable of maintaining telomeres, a ribonucleoprotein reverse transcriptase.

Telomerase, a RNA-dependent DNA polymerase silent in most normal human somatic cells, is frequently activated during the oncogenic process [18], [19].

However, telomerase is not expressed in most normal human somatic cells making them vulnerable to the aging related replicative senescence and potential telomere dysfunction during crisis that has been implicated in carcinogenesis [1], [19].

The expression of telomerase is suppressed in most normal human somatic cells, but is reactivated during tumorigenesis.

While hTERT is not expressed in most normal human somatic tissues, hTR is expressed constitutively in most human tissues (Kim et al, 1994; Shay and Bacchetti, 1997).

Telomerase activity, while not detectable in most normal human somatic cells, is associated with approximately 85% of malignant human cancers overall, including over 90% of breast cancers.