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In contrast, MET accumulation in MET PET reaches a plateau in most normal organs.
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Cell adhesion molecule integrin αvβ3 is highly expressed on activated endothelial cells and tumor cells but is not readily detectable in resting endothelial cells and most normal organ systems [157, 158].
These integrins are highly expressed on activated endothelial cells and tumor cells but are not present in resting endothelial cells and most normal organ systems; in particular their expression on the neoplastic blood vessels is known to be upgraded [34], [35].
The strongly increased uptake of FDG in cancer cells contrasts with most normal cells and organs.
However, a biodistribution assay for Cu-cyclam-RAFT-c -RGDfK- 4 showed that the radioaCu-cyclam-RAFT-c -RGDfK- 4t of the normal organs of the TSU-68-treated miCu-cyclam-RAFT-c -RGDfK- 4ed.
Besides clear tumour targeting, Br-L19-SIP also showed persistent activity in blood, stomach and several other normal organs, most probably due to in vivo debromination.
Instead, most are downstream effects of suppression of VEGF signalling in endothelial cells of normal organs.
And the most "normal".
Most normal schedules have disappeared.
No visible cross-reactivity with normal organs was observed.
Few studies report nanoparticle-mediated radiotoxicity to normal organs.
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