Sentence examples for most nonsynonymous polymorphisms from inspiring English sources
Thus, the high ratio of nonsynonymous to synonymous polymorphism is not limited to external branches, as would be expected to occur if most nonsynonymous polymorphisms were deleterious.
Segregating derived duplications were also found at lower frequency than nonsynonymous polymorphisms in most replicons (the exceptions were S. meliloti pSymB and the S. medicae chromosome) and genome-wide (table 4 and fig. 3), but these differences between nonsynonymous sites and duplications were statistically significant only in S. meliloti (table 4).
On the other hand, πS > πN is expected in the case of real polymorphisms because most nonsynonymous mutations are deleterious and are eliminated by purifying selection (Hughes 1999).
Again, relaxation of selection in L. montandoni is more likely: TLR21 is the most variable of all TLR genes and nonsynonymous polymorphisms are still segregating in all codons identified as positively selected by gammamap.
Most strikingly we find that PARP4 (also dubbed vault-PARP [64]) has numerous high frequency nonsynonymous polymorphisms.
Our studies have revealed that porcine PRR genes possess many nonsynonymous polymorphisms, particularly in regions encoding the ectodomains of TLRs localized on the cell surface.
The genes encoding TLRs located on the membrane of intracellular compartments, and cytoplasmic PRRs such as NLRs and RLHs, also possessed nonsynonymous polymorphisms.
Only two nonsynonymous polymorphisms were found in our sample, so other neutrality tests were not applied.
Common nonsynonymous polymorphisms in TLR6-TLR1-TLR10 TLR6-TLR1-TLR10 TLR6-TLR1-TLR10ted with TB disealsoin certain ethnic groups.
It appears that Neanderthals might also have had a significant excess of nonsynonymous polymorphisms in CYTB within their lineage.
Rare nonsynonymous polymorphisms in TLR6-TLR1-TLR10 TLR6-TLR1-TLR10 TLR6-TLR1-TLR10ted among African-American TB cases compared were ethnically-matched control significantly
