Sentence examples for most new mutations from inspiring English sources

Most new mutations are neutral with respect to survival and reproduction and therefore are irrelevant in terms of natural selection (but not, it must be pointed out, to evolution more broadly).

Whereas an accurate understanding recognizes that most new mutations are neutral or harmful in a given environment, such naïve interpretations assume that mutations occur as a response to environmental challenges and therefore are always beneficial (Fig. 2).

While it is generally assumed that most new mutations accumulate through the process of heteroplasmy, it is unknown whether mutations initiated in the mother are inherited, occur in utero, or occur and accumulate early in life.

As early as 1930, Fisher had indeed realised that most new mutations are detrimental [ 23].

Propagation of genetic information throughout families will not permit the detection of most new mutations.

Because most new mutations arise when the population is large, selection within the colony is minimal.

We propose that the occurrence of one highly deleterious mutational event (i.e. the ψND5-2 insertion and associated ND5 deletion events) presents a novel mutational target in the mitochondrial genome where most all new mutations are expected to reduce homology between ψND5-2 aND5ND5, thus reducing the likelihood of deleterious mitochondrial genome deletions.

Vogelstein predicts that most new driver mutations will be rare; and nearly all will be part of same 12 pathways.

One of the most common new mutations, in malE, may provide a benefit by reducing the load imposed by the malT mutations widespread in the population.

Most of the new mutations appear to be ephemeral and can be lost from a population or species during population contraction (the glacial maximum).

After verifying mutations known to be present in the strains at the outset, we identified new mutations most easily by comparing the sequence of each individual strain to a composite of the others.