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Most mutations occurred in loop regions.
Most mutations occurred by passage 5 and all mutations were observed by passage 15.
Most mutations occurred within the transcriptional attenuator region; the most frequently observed profiles were +22 C>T, +26 T>G, +27 A>T, +32 G>A, and +70 C>T (11 strains).
Most mutations occurred in one sample (322 mutations, 57 %) but some were observed in two samples (64 mutations, 11%%), there samples (18 mutations, 3%%) and four or more samples (11 mutations, 2%%).
Similar(56)
This gene is mutated in approximately 20% of CRC patients [ 85] with most mutations occurring in exon 9 and exon 20 [ 86].
Most mutations occur when DNA divides.
Most mutations occur spontaneously and have no known cause.
Unlike HPE due to mutations in other genes, most mutations occur de novo and the distribution of HPE types differs significantly from that of non-ZIC2 related HPE.
Because most mutations occur during the creation of new eggs and sperm, species with longer generation times should have slower molecular clocks.
In patients with imatinib-naïve GISTs, most mutations occur in the juxtamembrane (exon 11) or extracellular domain (exon 9) of Kit.
Most mutations occur within the kinase domain of the ZAP-70 protein, and significantly affect both protein stability, and catalytic activity.
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