Sentence examples for most mutations found from inspiring English sources

Most mutations found in OS patients cluster in the C-terminus of the protein [1], [3], [12] [17] and lead to the loss of microtubule-association of these proteins [10].

Most mutations found in papillary thyroid carcinoma involve the common signaling pathway involving RET/PTC-RAS-BRAF.

While most mutations found in HGD targets were high clonality, mutations found in non-dysplastic histological classifications (intestinal metaplasia, "indefinite for dysplasia") were typically low clonality.

In sporadic infiltrating lobular carcinomas (ILCs), most mutations found in the CDH1 gene were out-of-frame, which were predicted to yield secreted truncated E-cadherin fragments.

Notably, most mutations found in TBX5 are located in the DNA-binding T-box domain and a substantial fraction causes premature stop codons.

The results, summarized in Table  1, show that most mutations found in the superior 16D alleles are not uncommon in other yeast strains.

The observation that most mtDNA mutations found in UC patients were homoplasmic in nature indicates that the mutated mtDNA had become dominant in the colorectal mucosa of UC individuals.

Lung cancer is the leading cause of cancer related deaths worldwide and mutation activating KRAS is one of the most frequent mutations found in lung adenocarcinoma.

Activating mutations in the luteinizing hormone receptor (LHR) gene are one of the most common mutations found in the gonadotropin receptor genes.

In most cases, mutations found in patients affected by DTDS led to loss-of-function of the DAT protein, often resulting in the complete lack of residual DAT activity11,13.

The 3243A>G mutation in the MTTL1 (tRNALeu) gene and the 8344A>G mutation in the MTTK (tRNALys) gene are the most common mutations found in mitochondrial encephalomyopathy, lactic acidosis with stroke-like episodes and myoclonic epilepsy associated with ragged-red fibers, respectively.