Sentence examples for most modifications are from inspiring English sources
Because most modifications are present in low stoichiometry and would typically be discriminated by MS detection, a prerequisite of examining any modification on a global scale is the development of highly efficient enrichment strategies prior to MS measurements.
Indeed, most modifications are present substoichiometrically (occupancy below 50%), meaning that roughly equal numbers of substrate molecules lack the modification.
Root etching was the most common biological modification, and the most frequent modifications are involved with the microenvironments of the surface to burial substrate.
The most commonly targeted amino acids are lysine and arginine, and the most studied modifications are methylation, acetylation, ubiquitylation, SUMOylation and phosphorylation, but many others have discovered, such as glycosylation and crotonylation [ 14, 15].
The current version of the health game would primarily benefit those already healthy and could negatively affect those that need the intervention most, so modifications are recommendable.
The authentication results performed on the test dataset are averaged and shown in Table 4; the most malicious modifications are correctly judged as inauthentic with average authRatio lower than 0.86.
It has been reported that most histone modifications are related to the positioning of nucleosomes [ 14, 15].
For telomeres, the most significant modifications are H2BK5me1 and H3K4me3 and the least significant are H3K36me3 and H3K9me3.
The most common modifications are fucosylation, synthesis of additional GlcNAc branches, and transfer of galactose (Gal) and sialic acid residues.
(see Methods for details) For centromeres, the most represented modifications are H4K20me3 and H3K9me3 and the least significant modifications are H3K4me1 and H4K20me1.
Most histone modifications are found within the N-terminal histone tails which protrude from the nucleosomes and are thought to be flexible and unstructured.
