Sentence examples for most microbicides from inspiring English sources

Today, most microbicides in human studies or on the drawing board contain anti-HIV drugs that cripple a critical viral enzyme.

Most microbicides (86% of those being tested to date) increase lubrication [ 23].

While genital epithelial findings are documented in a standardized manner in most microbicide trials, little is known about background rates and predictors for many types of genital findings.

IVC less than 1 h after sex is discouraged in most microbicide trials.

The challenge virus in this model is HSV-2, whereas HIV is the primary focus of most microbicide development efforts.

Most microbicide research is conducted by developed sponsor countries in developing host countries where the burden of disease due to HIV/AIDS is greatest.

While most microbicide trials have tied adherence measures to specific sexual episodes, one sub-study complemented the proportion-based measure of condom and gel adherence with a second measure based on participants' estimates of consistency over a longer (2-month) time period.

To date, most microbicide trials have measured product adherence at last sex, or as the proportion of sex acts covered during the past week, rather than the entire 1- to 3-month period between scheduled follow-up visits, assuming that the more proximal the time reference, the more accurate participants' recall of events.

To date, most vaginal microbicides under clinical investigation have been formulated as single-dose semi-solid gels, designed for application to the vagina before each act of intercourse.

Hopes for the most promising microbicide candidate were dashed last year when a spermicide, Nonoxynol-9, appeared to increase H.I.V. transmission in human trials rather than reducing it.

As has been the experience with most investigational microbicide gels [18] [26], most of the participants in the IDIs and FGDs said the gel had increased their sexual pleasure and improved their relationships.