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At low pH, most metal complexes disassociate, which should minimize the quenching of fluorescence due to metal complexation [23].
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Most synthetic metal complexes used as antitumor chemotherapeutic compounds are structural analogs of cisplatin.
Most presently known metal complexes used for OLEDs contain the chelate cycles including the C-O-M-N chains [1 6, 9 11].
In this review we focus on the most relevant scorpionate-containing metal complexes that have been explored in the area of medical imaging and therapy.
In the case of most of the transition metal complexes intersystem crossing from the excited S1 to T1 state is close to unity and predominant emission process is phosphorescence.
They can serve as catalysts or catalyst precursors for hydrogenation and transfer hydrogenation reactions in water and they are at present one of the most promising classes of metal complexes to replace cisplatin in future cancer therapy, due to their inherent cytotoxicity and their good cellular uptake, conditioned by well balanced lipophilic and hydrophilic properties.
Structural analogs of cisplatin, the most widely used synthetic metal complexes, show toxic side-effects and tumor cell resistance.
The drug 1,10-phenanthroline is a heterocyclic organic compound that forms strong complexes with most metal ions [ 57].
This chapter begins by pointing out that homogeneous catalysis using transition metal complexes is the most important consequence of organometallic chemistry.
Considering that the most of the absorption bands of metal complexes are located in the low-frequency region [32], it is obvious that this absorption band is associated to complexes involving LiClO4.
4– 7, 8 Both the ROP of cyclic lactones and the ROCOP of epoxides/CO2 require catalysts; the most successful of these are homogeneous metal complexes.
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