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Most malignant lung and HNSCC lesions showed aberrant FHIT expression, reduced or absent p21 and increased cell proliferation.
In most malignant lung nodules, the interface is well-defined and coarse; this is mainly attributable to an infiltrative tumor growth pattern [ 13],[ 14].
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In the present study, we focused on non-small cell lung cancer (NSCLC), the most common malignant lung tumor, in particular its two major histological subtypes, adenocarcinoma (AC) and squamous cell carcinoma (SCC).
Brain metastases are one of the most malignant complications of lung cancer and constitute a significant cause of cancer related morbidity and mortality worldwide.
Lung cancer is one of the most malignant cancers.
Lung cancer is one of the most malignant tumors, representing a significant threat to human health.
doi: 10.1038/sj.bjc.6600327 www.bjcancer.com © 2002 Cancer Research UK Primary lung cancer is one of the most malignant solid tumours.
Lung cancer is one of the most malignant tumors and represents a significant threat to human health.
EGFR was found to be transcriptionally active in very many epidermal tissues, including healthy and malignant lung tissues, which is as expected from one of the most influential epithelial growth factor receptors.
The two most used methods to analyse 18F-FDG PET data for distinguishing benign from malignant lung nodules are either by subjectively assessing FDG avidity in comparison to background or using semi-quantitative analyses, SUV, most commonly SUVmax, with variable thresholds used as a cut-off to separate benign from malignant disease.
Serial analysis of gene expression (SAGE) profiles of non-malignant and malignant lung samples were compared using a permutation test to identify the most stably expressed genes across all samples.
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