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Metastasis-associated gene 1 overexpression is associated with the most malignant behaviour in several human tumours.
A correlation between gain of 6p and the most malignant behaviour in Rb has been proposed (Oliveros and Yunis, 1995) and a relationship between N-MYC amplification, higher proliferation index (PI), advanced tumour stage and poor clinical outcome was suggested (Kim et al, 1999).
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In breast tumour biology, deregulated proliferation is one of the most important features predicting malignant behaviour (Desmedt and Sotiriou, 2006).
This mutation results in a constitutively activated KIT tyrosine kinase and leads to increased malignant behaviour in most affected tumours [ 1].
doi: 10.1038/sj.bjc.6600476 www.bjcancer.com © 2002 Cancer Research UK At present, melanoma belongs to the most malignant tumours of the skin and mucous membranes due to its aggressive biological behaviour and tendency to generate early metastases.
The most malignant force is Newark's violence.
Gastric carcinoma is the most malignant tumor.
Predominantly solid adnexal masses account for lesions with benign, borderline and malignant behaviour.
Gliomas are one of the most malignant cancers.
Cardinale et al. [15] described the CT features of 26 SFTs of the pleura with benign and malignant behaviour.
At the most malignant, alcohol.
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