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Most lipid parameters decreased slightly from baseline but there were no significant differences between treatment groups.
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Most lipid profile parameters and ratios, except for LDL-C and TC, showed a considerable tendency for returning to pre-run values 48 h post race.
Population characteristics in Table 1 show that offspring and controls were similar in terms of age, BMI, and most classical lipid parameters except for total triglycerides and the TG-HDL-C ratio whose values were higher in controls (P < 0.005).
While some researchers have reported triglyceride to be the most predictive lipid parameter for CVD, in a recent meta-analysis by the Emerging Risk Factors Collaboration, such risk association was not confirmed after controlling for other confounders [ 23].
Subjects in the present study showed a markedly higher BMI (means: 31.8 versus 26.4 kg/m) and insulin resistance index (HOMA (means): 3.78 versus 1.82), lower adiponectin levels (means: 2586 versus 10844 ng/ml) and, considering these differences, most likely higher lipid parameters (Stefan et al. [ 27] did not present actual lipid data in their manuscript).
The NES implant had little important effect on most clinical chemistry and lipid parameters.
Fluvastatin (40 mg)+bezafibrate was the most effective for all lipid parameters with a decrease from baseline at endpoint in LDL-C of 24%, a decrease in triglycerides of 38% and an increase in HDL-C of 22%.
Interestingly, DHA containing lipids were among the lipids most significantly correlated with classical lipid parameters.
Most of the changes from baseline in lipid parameters were observed at week 26, with only small further increases through week 52.
The most likely explanation for the lack of effect on lipid parameters in our study is the lower amount of walnuts consumed (15 grams daily) compared to previous trials.
Most antidiabetes agents do not have a significant adverse effect on BP or lipid parameters.
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CEO of Professional Science Editing for Scientists @ prosciediting.com