Sentence examples for most likely pathogenic from inspiring English sources

In this investigation we implemented multiple computational methods to identify the most likely pathogenic mutations in TYRP1 gene.

However, another splice variant (c.1961_1963del) in patient RB24 as predicted as most likely pathogenic did not co-segregate with phenotype.

A filtering algorithm was applied to exclude all but the most likely pathogenic variants (Supplementary material), which were verified by PCR amplification and Sanger sequencing.

Using array-CGH, we have identified the first mutation affecting the regulatory region of GDF9 in a patient with SA, most likely pathogenic.

Considering only the most likely pathogenic variations (truncating, stop, and frameshift), a prevalence estimate of 9.6% of distinct EYS variants in the Spanish arRP population can be drawn.

We suggest that RA SF MDSCs are able to limit the expansion of joint-infiltrating (and most likely pathogenic) T cells.

Insulin resistance (IR) is the most likely the pathogenic link between PCOS and MetS.

For example, a novel intronic variant (c.265-9 c.265-9in paTient RB4 creates a cryptic splice site and is most likely a pathogenic variant.

Of these, six mutations (G36R, H180Y, P182L, A237S, N372S and V406I) are most likely non-pathogenic [42].

Nonetheless, these three variants are most likely non-pathogenic, since they have been found both in cases and healthy controls (Tables 2 and 3).

Of special note are our results indicating that ATBF1 variants showing differences in the length of amino acid repeat sequences are most likely non-pathogenic and instead are normally occurring polymorphisms.