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NMR and docking experiments suggest that heme IV is the region of interaction with similar physiological partners, while the other interacting partner would most likely interact through the region near hemes I and III.
In all likelihood, you'll most likely interact with at least one founder during your interview process.
Thus, the isolation of exosome subunits by purifying different Ccr4-Not subunits besides Not5 suggests that these exosome subunits most likely interact with the integral Ccr4-Not complex.
Taken together, these data indicate the partial co-localization of LRRK2 and Dnm1 in or adjacent to early endosomal compartments, suggesting that these proteins most likely interact at the cytoplasmic face of endosomal vesicles.
The EFBA approach integrates the information-processing methods with the seed-and-grow strategy to determine the probability distribution of the nucleotide sequences that most likely interact with target structures.
Collectively, these data indicate the partial co-localization of LRRK2 with dynamin-related GTPases and suggest that LRRK2 and Drp1 most likely interact within the cytoplasm whereas LRRK2 and Mfn1, Mfn2 and OPA1 interact at or adjacent to mitochondrial membranes.
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This couple most likely interacts like this on a regular basis and has boiled their relationship to generic apathy.
Interestingly, DMSO indiscriminately formed hydrogen bonds with water and most likely interacted with bulk water molecules.
By aligning the amino acid sequences of PHD3KDM5B, PHD3Lid and other PHD fingers that recognize the H3K4me2/3 peptide (Fig. 5), we found that the residues most likely interacting with the H3K4me2/3 site are highly conserved.
In this regard, the predicted disordered amino-terminal region of DNMT1 binds several proteins, including Rb and MeCP2 [33] and most likely interacts with DNA [13].
This indicates that GEF16 most likely interacts with Tip-1 via its carboxyl-terminal PDZ domain.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com