Sentence examples for most likely impairs from inspiring English sources

In this bird, even the outline of the vane (the flat, broad part of the feather) is quite irregular and in some feathers, the vane is twisted toward the tip--a luxury that most likely impairs the bird's ability to fly.

In sum, disrupted methylarginine metabolism most likely impairs vascular homeostasis in PAH, but it remains unclear, which DDAH or PRMT isoforms control ADMA tissue and plasma levels under pathological conditions.

Epigenetic silencing of OCT1 in hepatocellular carcinoma, as demonstrated by Schaeffeler et al. [ 4], most likely impairs uptake of some anticancer drugs into hepatocellular cancer cells and thus is likely to impair their efficacy.

This effect is most likely mediated by the inhibition of ribonucleotide reductase by Gemcitabine, the resultant reduction in dATP levels and the subsequent misincorporation of nucleotides into DNA; in MMR deficient cells, the removal of these misincorporated bases is reduced, which most likely impairs the fitness of cells.

In summary, there is a growing body of evidence that IL-1 β and TNF α in optimal concentrations are important for stimulation of axonal growth and recovery of functional innervation after nerve injury and that neutralization of these proinflammatory cytokines most likely impairs peripheral nerve regeneration [ 12].

Carbo-Iron may exceed these effect concentrations in treated aquifers, but the presence of the pollutant has most likely impaired the quality of this habitat already.

Since the most recent outbreaks, disturbance frequency was high with recovery most likely impaired by bleaching in 2002.

A DNA maintenance or repair pathway is most likely impaired.

Hence, the mitochondrial defects in Pattern III lesions most likely impair activity, assembly and stability of complex IV.

More specifically, STCA covalently reacts with Cys-412, Cys-564, and Cys-589 (or Cys-590) in human recombinant Hsp90, most likely impairing its chaperone activity, leading to Hsf1 release and HSR activation [ 72].

On the other hand, the segmental chromosomal alterations in high- and intermediate-risk tumours are most frequently due to unbalanced chromosomal translocations, which in turn are thought to arise from improperly repaired DNA double-strand breaks, suggesting that a DNA maintenance or repair pathway is most likely impaired.