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Thus, we concluded that the rhamnose group found in quercitrin is most likely essential to the antivenom activities of this flavonoid against C. d. terrificus sPLA2.
No other mutants with a comparable phenotype were recovered, presumably because other protein kinases involved in regulating gliding and midgut invasion, such as CDPK1, PKB, and PKG, are most likely essential in the merozoite and could not be deleted.
Because of the purine bias, the ancestral codon pattern is RWY and not RNY, which indicates that the amino acids Asp, Val, and Ile (GWY) were most likely essential for the formation of functional proteins under prebiotic conditions.
This core set of ORFs contains many of the housekeeping and subunit proteins and enzymes previously described as most likely essential in the WB_A1 genome (Morrison et al. 2007).
By combining these results, we developed a novel way of predicting residues that are most likely essential for the catalytic activity of the protein based on their degree of conservation.
This phenomenon has occurred in several MMTV-PyV mT/MMTV-Cre recombinase backgrounds as demonstrated by our own laboratory: conditional ablation of β1-integrin, focal adhesion kinase, c-Src or Stat3 was prevented, indicating that in each case the conditional gene was most likely essential to PyV mT-driven tumourigenesis [ 5- 7] (unpublished observations; Ranger JJ, Muller WJ).
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Although its commercial prospects are most likely slight, "Essential Killing" deserves to be seen and further discussed and might well receive a limited American release.
The broad point of this new notion is that if physical activity helped to mold the structure of our brains, then it most likely remains essential to brain health today, says John D. Polk, an associate professor of anthropology at the University of Illinois at Urbana-Champaign, and co-author, with Dr. Raichlen, of the new article.
These four genes most likely perform essential functions during the infection of hosts.
Although the NE pool of Mps3 is most likely not essential for growth, it serves as the SPB reservoir (Bupp et al. 2007; Gardner et al. 2011).
This property has meaningful biological implications in the context of promoter dynamics and is most likely an essential feature of eukaryotic promoters (see Results).
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