Nevertheless, we must point out some weaknesses of the intervention that most likely diminished its efficacy.
Increasing screening participation to obtain an even higher degree of coverage will most likely increase the efficacy of the screening programme in decreasing the incidence of cervical cancer.
Second, the study sample included patients starting antiretroviral treatment from 2003 to 2011, during which period prevention policies and treatment programmes have undergone many significant changes that have most likely influenced treatment efficacy.
It is possible to estimate an effective field efficacy, which is the value of the individual efficacy most likely to yield an observed prevalence curve given constant transmission rates over the observation period and the antibiotic coverage.
While active against multi-drug resistant (MDR) strains in vitro, octapeptin C4 displayed poor in vivo efficacy, most likely due to high plasma protein binding.
The superiority of Indoprocaf compared to sumatriptan in this in vivo model supports the recent clinical evidence that Indoprocaf most likely has similar therapeutic efficacy to sumatriptan [31, 32], recognizing therefore the role of Indoprocaf in the acute treatment of migraine.
This is most likely due to the efficacy of high-dose chloroquine as used in Guinea-Bissau, combined with a loss of fitness associated with pfcrt 76T.
Although the concentration of the compounds inside the nematode is probably lower than in the media, the ratio between the MIC and the EC50 provides a way to identify compounds that most likely have a higher efficacy in vivo than in vitro.
With the same dose of the drug isoniazid, the 50% slow acetylators have high blood concentrations and, most likely, a better antibacterial efficacy, but they may have more adverse effects.
It was concluded that optimal fracture efficacy most likely required more substantial increases in BMD, as well as more pronounced suppression of bone turnover and that this required higher iv doses of ibandronate.
