Sentence examples for most likely cell from inspiring English sources

We further show how these integrated functional scores can be used for (1) deriving the most likely cell or tissue type causally implicated for a complex trait by using summary statistics from genome-wide association studies and (2) estimating a tissue-based correlation matrix of various complex traits.

The exact molecular nature as well as the hierarchy of their interaction is most likely cell- and context-dependent and can not be generalized.

Given their direct spatial relationship with hematopoietic cells, hepatic progenitors are the most likely cell type that assembles the FL hematopoietic microenvironment in concert with other stromal cell populations.

Further studies are needed to determine the specific types of cells moving within all EP bridges, but based on the composition of EP islands the most likely cell types migrating via these conduits are Clara cells and undifferentiated, transitional EPs.

Of these, most likely, cell cycle synchronization [ 7, 60, 61] and DNA repair [ 32] play an important role in the radiosensitisation.

Further studies using the cyclin D1 promoter indicate that c-jun upregulation by estrogen may induce cyclin D1 expression and most likely cell cycle progression.

Importantly, RASSF1A CKO mice had better cardiac function after pressure overload compared to controls, indicating that RASSF1A function is most likely cell-type-dependent.

Most likely, cells of the core area are not susceptible to PPADS treatment, because of the severity of the ischemia, which is still aggravated by a limited collateral circulation known to exist in this rat strain used.

Because in situ hybridisation experiments showed that Sesn2 mRNA expression was confined to the subepithelial bronchial space, where it colocalised in part with smooth muscle actin (α-SMA), suggesting expression by myofibroblasts (supplementary material Fig. S8), the beneficial and deleterious effects of superoxide anions are most likely cell-type specific.

Cells found within prostatic lumen which were positive for active caspase 3 were most likely cells undergoing apoptosis after terminal differentiation, or anoikis, once they had shed into the lumen, as discussed in Debnath et al., 8. 3D breast epithelial cell cultures undergo a massive apoptosis of the central cells or cavitation event to form luminal spaces within acini.

As shown in Fig 5, mainly epithelial cells were TUNEL-positive, although some cells beneath the bronchi, most likely inflammatory cells and mesenchymal cells, were also TUNEL-positive.