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In some projects, we use colocalization methods to systematically prioritize the most likely causal gene in loci associated with insulin resistance and related traits (such as fasting insulin, glucose, waist-hip ratio, HDL cholesterol and triglycerides).
Furthermore, using path analyses, we explored the most likely causal relationships between habitat, emotional behavior and innovation.
The higher density of informative markers in the MDP population may help to select the most likely causal gene.
Hierarchical partitioning (HP) is an analytical method of multiple regression that identifies the most likely causal factors while alleviating multicollinearity problems.
Thus, even though the MDP data do not always correctly predict the most likely causal gene, the data substantially improve the gene selection.
These qualitative differences in the types and numbers of different predators are the most likely causal factors behind the parallel phenotypic divergence in two of the most intensively studied lakes [18].
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While it is likely that the diseases of interest in this investigation act in different biological causal pathways, if acting independent of tobacco exposure, however, the inflammatory response is the most likely common causal link [97].
These QTL genes are most likely the causal genes based on the following evidence.
Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region.
We have annotated our set of statistically significant SNPs in order to prioritize the most likely candidate causal variants within each region.
This approach can be complemented by trans-ancestral mapping with the most likely common causal variant (that is, the effect identified by Köttgen and colleagues) predicted to be most strongly associated with urate levels (and gout) between diverse ancestral groups.
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most likely accidental
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most likely etiologic
most likely incidental
most likely causative
most penetrant causal
most likely dead
most significant causal
most suspected causal
most frequent causal
most prevailing causal
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