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In line with the above arguments we sorted the predicted high score motifs into three subclasses in descending order of reliability (Table S5): The most likely binders, 110 binding motifs contributed by 98 proteins, belong to class A where all residues of the motifs are present either in the phage selected pool or in known DYNLL binding motifs suggesting no energetic obstacles for binding.
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Most likely to: Sound sweet like chocolate.
To aid more successful targeting of PPIs, it is important to focus efforts onto those PPIs that are most likely to yield high-quality, high-LE small molecule binders, i.e., exhibit highest druggability.
Use of the non-absorbable phosphate binder sevelamer can also decrease serum urate in haemodialysis patients, most likely the result of increased gastrointestinal elimination [ 21].
This is most likely due to preferential liquid penetration into the fine pores related to the dry binder particles and subsequent partial softening and dissolution of the binder.
Most likely.
Mid-seventies, most likely.
The most likely outcome?
"Most likely a hawk.
Most likely neither.
For Torrie, most likely..
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