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(Note that this problem can also be understood as finding the most likely assignment of points in a clustering task. Specifically, consider mixture of Gaussian clustering of three two-dimensional points into two clusters with unknown means).
Shown are the fraction of genes (y axis) whose probabilities of the second most likely assignment is less 30%, 50%, or 70% of the most likely assignment, that is q/p
The most likely assignment occurs at k = 5, with four distinct populations coinciding with named varieties (Fig. 5B).
This general agreement also is very positive because previous simulation methods have suffered from upward bias in their assessment of most likely assignment power (Anderson 2010).
Haplotypes were assigned to subjects using the SNPHAP software (see [ 13]), which also reports the posterior probability of the most likely assignment [ 14, 15].
Furthermore, the probabilities associated with the second most likely are less than 70% of most likely assignment for approximately 90% of genes (60 80% for C. albicans, D. hansenii, Y. lipolytica and the Schizosaccharomyces species; Author response image 1B).
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Additional file 1 lists the most likely assignments for the compounds in the solution.
The most likely assignments based on the fragmentation pattern of individual peaks obtained from mass spectrometry are listed in Additional file 2. Products such as toluene are direct evidence of chain breaking and aromatization reactions in presence of oxygen.
Most likely assignments are indicated by bold font.
Discrete copy number profiles can also be queried as the most likely assignments of the latent copy number variables given observed data.
Fugue does not use predicted secondary structure to determine either the most likely family assignment for a given sequence nor the alignment, and so the correlation gives increased confidence in the fold assignment and alignment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com