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Most lethal prostate cancers progress from relapse of aggressive primary disease.
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However, hormonal therapy is only temporizing and invariably leads to the development of hormone-refractory prostate cancer (HRPC), the most lethal form of prostate cancer.
Tumour invasion and metastasis remains the most lethal aspect of prostate cancer (Jaeger et al, 2001).
Prostate cancer is the second most lethal tumour among men, and Ca2+ has been shown to be essential for increased cell proliferation in advanced prostate cancer (PCa) cells [ 2– 4].
Although prostate cancer is the second most lethal cancer in the Western world, its pathogenesis is relatively poorly understood at the genetic level.
Lectins have shown the ability to recognise these modifications in several carcinomas, namely in the prostate carcinoma, one of the most lethal diseases in man.
Prostate cancer ranks as the second most lethal malignancy in the Western world.
Prostate cancer (PCa) is the second most lethal tumor among men, wherein the major hallmark is the acquired resistance to apoptosis rather than enhanced proliferation.
Prostate cancer (PCa) remains the most common and second most lethal tumor in males in the Western World [1].
Prostate cancer remains the most common noncutaneous human malignancy and the second most lethal tumor among men with the highest incidence in industrialized countries [1].
DOI: http://dx.doi.org/10.7554/eLife.00499.001 Prostate cancer is the most commonly diagnosed cancer in men, and the second most lethal.
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CEO of Professional Science Editing for Scientists @ prosciediting.com