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Pancreatic carcinoma is one of the most lethal neoplasms, with an overall 5-year survival rate < 5% [ 1, 2].
Carcinomas of the oesophagus and stomach remain among the most lethal neoplasms leading to nearly 1 million deaths annually world wide.
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High-grade serous ovarian carcinoma (HGSOC) is the most lethal gynecologic neoplasm, with five-year survival rate below 30%.
Ovarian cancer is the most lethal gynaecological neoplasm, accounting for over 6% of deaths from cancer in women [ 1].
ATC is one of the most lethal of all human neoplasms.
Kidney cancer, which accounts for 2 3% of all adult malignant neoplasms, is the most lethal of the urologic cancers.
Gallbladder cancer (GBC) is one of the most lethal malignancies and the fifth common neoplasm of gastrointestinal tract [ 1– 3].
Glioblastoma is the most lethal primary malignant brain tumor.
Hepatocellular carcinoma (HCC) is the sixth most common neoplasm, and the third most lethal accounting for more than 600 000 deaths per year worldwide (Parkin et al, 2005).
Glioblastoma (GB) is the most frequent primary brain neoplasm and one of the most lethal tumors.
Renal cell carcinoma (RCC) is the most lethal urological disease [ 1] and is responsible for 3% of all malignant neoplasms [ 2].
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