Sentence examples for most large trials from inspiring English sources

Nevertheless, the study reported by Van den Berghe et al. [ 25] is certainly a major step forward in the treatment of critically ill patients, particularly in the context of failure of most large trials on the value of immunomodulatory treatment of sepsis and shock to show a beneficial impact.

Apart from most patients being pretreated for metastatic disease, the distribution of main features is roughly comparable with that from most recent large trials of first-line biochemotherapy (Eton et al, 2002; Ridolfi et al, 2002; Bajetta et al, 2006).

Most large clinical trials are scientifically valid.

Most large clinical trials for human immunodeficiency virus (HIV) conducted at university medical centers require intensive real-time monitoring, with clinic visits at least every 4 to 8 weeks.

Nevertheless, most large CRT trials applied some form of AV delay optimization [ 1– 3, 18].

The planning process for GRADE differed from that for most large, multicenter trials sponsored by NIDDK.

The survival observed in our study appears consistent with that observed in most large randomised trials.

Most large clinical trials are powered to find a clinically meaningful difference between treatment and control groups around 80-90% of the time.

The choice of 5% was conservative when compared with the targeted difference in protein intake in most large randomised trials that is 10% or more.

Despite this increase of diabetes and its complications in older adults, until recently, older adults were poorly represented in most large diabetes trials.

Lipids were measured using standard techniques, with most large, multicentre trials using one or two central laboratories and quality control procedures.