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Eccrine sweat glands are skin-associated epithelial structures (appendages) that are unique to some primates including humans and are absent in the skin of most laboratory animals including rodents, rabbits, and pigs.
In most laboratory animals monooxygenases are apparently absent or barely detectable in fetal organs until just before birth.
XendoU is known to be broadly conserved among Metazoa, but its homologues in human and most laboratory animals remain hypothetical.
Arsenic is rapidly metabolized after ingestion of iAs from drinking water and is excreted mainly through the urine in humans and most laboratory animals (Vahter 1999, 2000).
An accumulating body of evidence now indicates that human AhR signaling is less operative than AhR function in most laboratory animals.
Fritsche and colleagues found the AhR was not activated in the human test cells and wrote that "an accumulating body of evidence now indicates that human AhR signaling is less operative than AhR function in most laboratory animals".
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An understanding of MOAs is hindered by potential confounding factors in human studies and limited characterization of fibers in most laboratory animal studies (Mossman et al. 2011).
Sharing of best practice has already taken place for in vivo studies; this is especially important since it appears that the absolute change in QTc (in msec) is smaller in most laboratory animal species than in man.
And it's not because the fly is one of the most important laboratory animals in the history of biology, often used as a simple model for human genetics or neuroscience.
The rat ranks among the most important laboratory animals but few methylome studies have been performed in this species.
An effective animal model would greatly facilitate progress in this area, but most common laboratory animals (rat, rabbit, guinea pig, etc).
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