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The Gcm protein is structurally conserved, as are most key developmental factors present in the fly genome.
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This is of interest because for most lineages the key developmental regulators are activators, while in the neuronal lineage a key regulator is the transcriptional repressor REST NRSFF).
Remarkably, significant gene misexpression in backcross hybrids involved several genes, most notably the disruption of three key developmental genes involved in protein folding and mRNA translation.
The striking thing about the two most successful economies (and leading liberalisers) of the last two centuries Britain and America is that during key developmental stages they were unusually free from invasion fears.
The assessment of gene expression changes at key developmental periods of the life cycle, as well as at the ages most commonly used in pre-clinical drug safety testing, was the focus of this study.
What follows is a key developmental period for the foetus.
The expression of two key developmental genes, pou5f1 and cdx2, was significantly increased by CBHA treatment.
Retinoic acid (RA), the active form of vitamin A, regulates key developmental processes in multiple organs.
Human activation protein-2 gamma (hAP-2γ) is a key developmental transcription factor.
Polycomb group (PcG) proteins are conserved chromatin factors that regulate key developmental genes.
Polycomb group (PcG) proteins dynamically define cellular identities through epigenetic repression of key developmental genes.
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