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The phyletic retention measure was, as in yeast, found to be the most informative feature when ranking by conditional mutual information [ Additional file 1].
It is designed to find the most informative feature subset to facilitate data visualization, clustering, classification, and ranking.
Feature selection algorithms enable extracting the most informative feature sets to be included in the data-driven inference engine (or classifier).
The single most informative feature is the average ΔSASA.
Thus, the most informative feature increased the AUC by 0.2, the last six together by only one tenth of this.
To follow up on the observation that tree topology seems to be the most informative feature type, we examined how this feature varies between primary and metastatic trees.
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The most informative features (according to information gain [ 32]) were the nucleotides in the NAGNAG and its immediate vicinity, and even a relatively simple classifier like the Naïve Bayes classifier could match the more sophisticated Bayesian network and Support vector machine.
The performance of random forests using clinical measurements, clinical codes and their combination after selecting different proportions of the most informative features according to their information gain scores are shown in Figure 3 for accuracy and Figure 4 for AUC.
It ranks features according to certain information criteria and only the most informative features are used for classification.
When, e.g., setting the information gain parameter to 50, the fifty percent "most informative features" are kept, reducing the size of the resulting model.
Comparing with standard regression approaches with regularization, the proposed framework integrates the information theoretic criteria in the generalized Lasso model, and sets the most informative features penalty-free to improve prediction accuracy and enhance model interpretability.
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