PU values are known to be strongly associate with GC content of the motifs and the surrounding context [ 2], therefore it would be most informative to evaluate the difference in the distribution of PU values for the same group of elements surrounded by wild type and dinucleotide reshuffled contexts.
Similar to the distribution of methylation differences noted for the top 56 loci, the 1,000 most informative loci had a mean difference of 0.60 with a standard deviation of 0.20 log2 units.
This category "refers to a biological objective to which the gene or gene product contributes" [ 79] and therefore allows most informative linkage to ecological differences.
Although the marker selection methods explored in this study agreed to a large extent in identifying the most informative SNPs, there were differences in their performance in ancestry estimation.
However, at the same time, the non-pair correlation increased from 0.002 to 0.83 (±0.02) with all probes and from 0.009 to 0.59 (±0.05) with the most informative probes, overall lowering the difference in correlation between pairs and non-pairs.
The most informative linear model described only a population difference: the Laguna Mountain population displayed more restlessness than the population from UC-San Diego (with Laguna Mountain as reference: effect of population = -1299.4, p = 0.054; R = 0.102).
Of the parenting dimensions and practices, rules were most informative to identify binge drinkers, despite possible differences in strictness between parents' reports and adolescents' perceptions [ 13].
It has been suggested that differential neural activity in imaging studies is most informative if it is independent of response time (RT) differences.
Differences in ANKRD1 expression pattern were found to be most informative: ANKRD1 levels were associated with decreased cardiac contractility and compliance.
There exists an informal shortlist of plant traits that are thought to be most informative.
