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Almost 100 cattle have been culled over the past few days to stop the virus--one of the most infectious pathogens known on Earth--from spreading.
In the development of adaptive immunity to tumours and most infectious pathogens, professional APCs, such as DCs, are capable of presenting exogenous antigens to CD8 positive cytotoxic T lymphocytes in a pivotal process, which is known as antigen cross-presentation.
Although most infectious pathogens enter through mucosal surfaces [1] traditional immunization strategies, including the parenteral route, do not induce effective mucosal responses [2], [3].
Most infectious pathogens exhibit variation in virulence across space, time, or host species.
In addition, HSCs are resistant to most infectious pathogens with only few exceptions such as the human polyomavirus 2 (JC virus).
Coxiella burnetii is the causative bacterial agent of Q fever in humans and is one of the most infectious pathogens known.
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Francisella tularensis is the etiologic agent of the zoonotic disease tularemia and one of the most infectious bacterial pathogens known to humans and animals.
5 6 Surprisingly, a series of extra-gastric and even extra-digestive diseases, including haematological disorders such as idiopathic thrombocytopenic purpura and iron deficiency anaemia, cardiovascular diseases, as well as neurological disorders are associated with H pylori. 7 On a global scale, H pylori is the most infectious human pathogen, affecting about 50% of the population.
Influenza A virus (IAV) is the most common infectious pathogen in humans, causing significant morbidity and mortality in infants and the elderly.
Influenza A virus (IAV) is the most common infectious pathogen in humans and causes significant morbidity and mortality, particularly in infants and the elderly population [ 1, 2].
For a contrasting application of the method, I now focus on measles which was the most infectious of the pathogens studied in [1].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com