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Skeletal muscle represents the most important tissue for maintenance of balanced glucose homeostasis since it accounts for ∼80% of insulin-stimulated glucose uptake [4].
While the tonsil may be the most important tissue reservoir in carriers, it is not the only organ of concern.
RT is the most important tissue for rhizome development because they contain apical meristems consisting of pluripotent cells for rhizome initiation after embryogenesis.
Previous research has demonstrated that the midgut is the most important tissue as an organ of food digestion and nutrient absorption [ 25].
We have previously sequenced and characterized the P. fucata transcriptome from mantle tissue, which is the most important tissue during shell and pearl formation, with 58,623 unigenes (unpublished data).
However, in this study, our findings indicate that the salivary gland is more likely to be the most important tissue with regards to immune defense responses in N. lugens.
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However, it is often difficult to find regions of interest (ROIs) that contain the most important tissues in biopsy scans; therefore, more effort needs to be put into detecting ROIs from biopsy images.
In conclusion, the data we obtained, clearly indicate that ENPP1 exerts in vitro a direct detrimental effect on the most important tissues for insulin sensitivity, insulin secretion and, eventually, glucose metabolism.
Taken altogether, these findings clearly indicate that ENPP1, especially when the Q121 variant is operating, affects in vitro the most important tissues controlling glucose metabolism, including liver, skeletal muscle and insulin secreting beta-cells.
As one of the most important tissues, kidney plays an essential part in regulating many important body functions.
Bone is one of the most important tissues both for maintenance of architectural integrity and metabolic activity, which undergoes continuous remodeling.
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