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The most important subset are CD4+ cells that constitutively express the IL-2 α-chain (CD25) and Foxp3 [ 11].
Briefly, these techniques can identify from a sample of potential predictor variables the most important subset for categorizing subjects or predicting outcomes [ 58].
Indeed, primary tumor invasion (T) is the most important subset of the American Joint Committee on Cancer staging criteria; it determines the surgical approach.
For instance, this approach can be used in microarray studies to accurately identify the most important subset of polymorphisms even when the number of variables greatly exceeds the number of participants.
This technique is used in data mining where the goal is to identify the most important subset of variables in a large collection as, for example, in microarray studies.
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CD4+ T cells have long been favoured as the most important immune cell subset in the pathogenesis of disease, but there is increasing evidence that CD8+ T cells play a substantial role in central nervous system damage (reviewed in [ 1]).
Our analysis was the only meta-analysis focusing totally on severe sepsis and septic shock, which are the most important and specific subset of sepsis, and for that the analysis separated from previous meta-analyses studies.
Given that the number of different ICT and ITS (i.e. advanced) technologies used in railway systems is too large to deal with in the same paper, and considering that the TCIS are one of the most important of their subsets, having significant impact on railway transportation sustainability, we decided to focus only on these systems.
RNE finds the subset of most important neurons by iteratively removing neurons that least affect the accuracy of the NPC.
There has been dispute as to which of the HDL subsets are most important in protecting from atherosclerosis, with general agreement that high plasma levels of alpha1-HDLs and apoA-I are protective [ 13, 14].
For the time being the most important outcome predictors are genetic subsets, initial white blood cell count, age at diagnosis, and early treatment response measured by minimal residual disease (MRD) markers [ 4].
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