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Let us now examine what is probably the most important randomized clinical trial in intensive care: the lower versus higher tidal volume treatment in acute respiratory distress syndrome (ARDS) [ 12].
The most important randomized clinical trial providing information about this issue is the Women's Health Initiative (WHI) study [ 44] reporting increased risk of breast cancer in women who took estrogen plus progestin but not in women who took estrogen alone [ 45].
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The most important reason for randomizing the clinics instead of individuals – i.e. public health nurses (PHN) or pregnant and postpartum women – is the likelihood of contamination of the PHNs' counselling practices.
In the 1920s statistician and biologist Ronald Fisher discovered the most important principles behind A/B testing and randomized controlled experiments in general.
Guideline statements may be supported by evidence obtained from various study designs, but randomized trials are usually considered most important for making recommendations about therapeutic and preventive interventions.
Randomized controlled clinical trials (RCT) are widely considered one of the most important vehicles of discovery of new treatments.
Your most important job".
The most important element?
Most important is safety.
The single most important".
Most important, stuff happens.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com