Sentence examples for most important proteolytic from inspiring English sources

In particular, the Clp protease is one of the most important proteolytic system in the stroma [ 14].

MMP-2 is one of the most important proteolytic enzymes that degrade basement membrane and extracellular matrix during tumor invasion and metastasis [ 16].

The most important proteolytic ECM enzymes are matrix metalloproteinases (MMPs), and upregulated MMP expression has been demonstrated to be strongly associated with the progression of malignancy in several types of cancer, including NPC[ 31, 32].

To investigate the mechanism mediating the stimulation of invasive potential of PC3 cells by treatment with TGF- β1, we analysed the role of uPA, one of the most important proteolytic enzymes involved in tumour cell invasion (Festuccia et al, 1998), in this process.

The most important proteolytic ECM enzymes are metalloproteinases (MMPs), and upregulation of MMPs expression has been reported to be strongly associated with the progression of malignancy in several types of cancer, including NSCLC (Cox et al, 1999; Egeblad and Werb, 2002).

In particular, we focus on the ubiquitin-proteasome machinery and the autophagy-lysosome machinery, the two most important cell proteolytic systems that control protein turnover in muscle.

Perhaps, the most important mechanism is proteolytic removal of the prodomain by other endopeptidases such as furin (Pei and Weiss 1995).

Most studies suggest that the ubiquitin-proteasome proteolytic pathway is most important in intracellular proteolysis, although there have been no reports on the activity of this pathway in patients with different extents of weight loss.

The proteolytic enzymes are the most important group of commercially produced enzymes.

The most important effectors of these complexes changes are proteolytic systems active on component of the extracellular matrix.

The most important aspects of the biology and evolution of proteolytic C. botulinum have been highlighted by this study, particularly in relation to the neurotoxin and its associated cluster and the FGI.