Sentence examples for most important oncogenic from inspiring English sources

The phosphatidylinositol 3-kinase (PI3K /Akt pathway is thought to be one of the most important oncogenic pathways in human cancer.

Vaccines against the two most important oncogenic types of HPV (16 and 18) are now licensed.

In the second setting, Brn3a was studied in combination with V600EBRAF, the most important oncogenic alteration in melanoma, which is present also in nevi.

Both vaccines cover the most important oncogenic HPV-serotypes16 and 18, which are considered responsible for 70% of cervical cancers and the majority of non-cervical cancers caused by HPV [ 2].

In addition to ECS functions in order to maintain homeostasis, the above-mentioned cross-talk between the ECS and the most important oncogenic pathways (MAPK/ERK and PI3K/Akt pathway) has recently gained interest and has highlighted the significance of the ECS in tumorigenesis [ 12, 13].

One of the most important characterized EMT-inducing oncogenic changes is the K-RAS mutation [ 14, 15].

Protection against all oncogenic types is most important up to age 25 years, when the risk of exposure to HPV is greatest, and it is possible that this exposure may naturally boost and maintain protection.

Objective: Infection with oncogenic human papillomaviruses (HPVs) is the most important cause of cervical cancer worldwide.

Being able to discriminate tumour origins, subtypes, oncogenic mutations and cancer predisposition, and regulating the most important cellular processes, it is logical to hypothesize that miRNAs might be able to predict also cancer prognosis and/or response to specific therapies.

doi: 10.1038/sj.bjc.6600454 www.bjcancer.com © 2002 Cancer Research UK The most important risk factor for development of cervical carcinoma is infection with the oncogenic types of human papillomavirus (HPV).

The oncogenic transcription factor MYCN is considered to be one of the most important genes involved in the tumorigenesis of NB.