Sentence examples for most important modulators from inspiring English sources

We explain our results by the differential effects of the β-subunits, namely β2a and β2b as the most important modulators in recombinant assays.

The secondary metabolites are, therefore, the most important modulators of the oestrogen receptor in the tamoxifen pathway (Lim et al, 2005).

It is believed that PI3K/Akt is among the most important downstream signalling pathways and that VEGF is one of the most important modulators of effects.

Interleukin-2 (IL-2) was identified in 1975 as a growth factor for T lymphocytes and is now considered one of the most important modulators of the inflammatory response.

One of the most important modulators of intestinal epithelial cell differentiation is transforming growth factor-β (TGF-β), which affects the cell cycle machinery leading to terminal differentiation [ 1].

Especially the physiological time courses of 25(OH)D3 (Vitamin D) as well as PTH (Parathyroid Hormone) the most important modulators of calcium and bone homeostasis are not yet examined sufficiently.

Using these data reduction strategy, we narrowed down the miRNAs list, showing that miR-29a/c, miR-34b/c, miR-429, miR-203, miR-222, miR-1/206, miR-141, miR-18a/b, miR-544, miR-205 and miR-149 may be the most important modulator during the development of NPC.

Vascular Endothelial Growth Factor (VEGF) pathway has emerged as one of the most important positive modulators of Angiogenesis, a central process implicated in tumour growth and metastatic dissemination.

As example of miRNA affecting survival pathway, miR-17-5p has been identified as one of most significantly downregulated miRNAs in paclitaxel-resistant lung cancer cells, which might cause upregulation of beclin 1 gene, one of the most important autophagy modulators [ 153].

Although personal cigarette smoking is the most important cause and modulator of chronic obstructive pulmonary disease (COPD), secondhand smoke (SHS) exposure could influence the course of the disease.

Raloxifene is one of the most important selective estrogen receptor modulators currently employed for the treatment of postmenopausal osteoporosis.