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One of the most important methodological aspects of studies designed to investigate developmental drug exposure is the identification of the appropriate animal model.
In DEA, the most important methodological contribution has been made by Charnes et al. (1981), who developed DEA, a performance measurement technique which can be used to evaluate the relative efficiency of companies.
As mentioned in the previous section, the most important methodological issue concerning economics involves the very considerable simplification, idealization, and abstraction that characterizes economic theory and the consequent doubts these features of economics raise concerning whether economics is well supported.
One of the most important methodological problems in psychological research is assessing the reasonableness of null models, which typically constrain a parameter to a specific value such as zero.
Mill's vision survived the so-called neoclassical revolution in economics beginning in the 1870s and is clearly discernable in the most important methodological treatises concerning neoclassical economics, such as John Neville Keynes' The Scope and Method of Political Economy (1891) or Lionel Robbins Ann Essay on the Nature and Significance of Economic Science (1932).
Nevertheless, the most important methodological problem when working with microbial mats is the difficulty to evaluate changes produced on cyanobacterial populations that are found in thicknesses of just a few mm depth.
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Importantly, most trials have important methodological flaws and have used inconsistent methods and therapeutic endpoints [29].
Twardowski himself favoured descriptive psychology as basic, but many of his students found logic to be the most important source of methodological criteria for philosophy.
The most important technical and methodological aspects of each step and the essential elements of a good systematic review in laboratory medicine are presented.
Importantly, most trials have important methodological flaws and have used inconsistent methods and therapeutic endpoints [ 29].
The internal validity of the included RCTs was difficult to assess as most studies omitted important methodological details.
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