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HBsAg is the most important marker for laboratory diagnosis of HBV infection.
Overall, the mitotic count was the most important marker for tumor grade.
For almost 20 years, we and a few other coastal storm scientists have been urging the media to stop using the Saffir-Simpson Scale as the sole, or even the most important, marker for the magnitude of the threat from a hurricane.
Having an orgasm was ranked as the most important marker of 'having a good time' during sex, with other factors such as hygiene and mood also deemed necessary.
He found that at the point of a decision, emotion came in to play as the most important marker to determine the outcome.
In theory, labor could back candidacies by competing Democrats, but they'd have to run against incumbents who have spent years building fundraising networks and potentially alienate fellow Democrats for whom the trade bill is not the most important marker.
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But the most important markers of whether you shop at Ikea (until now anyway) is whether you are a driver.
One aspect that has become more and more relevant over time, and one that youth today considers one of the most important markers of adulthood, is the achievement of economic (and residential) independence.
But I think Tchaikovsky deserves that irresistibly over-the-top conclusion: his First Symphony is one of the most important markers in the symphonic story in the 19th century, the piece in which a new type of symphony – absolutely Tchaikovsky's own, and Russia's too – is not just glimpsed, but claimed, staking out the territory his next five symphonies continued to explore.
Of those, the most important markers are Web Sockets and Web Workers — which, to oversimplify things, respectively allow for two-way communication between web sites/devices (for realtime functionality) and for multiple scripts to run simultaneously locally on the device.
Despite its apparent simplicity, HRV is one of the most important markers of the autonomic nervous system activity and it has been recognized as a useful predictor of several pathologies.
More suggestions(15)
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com