Sentence examples for most important downstream from inspiring English sources

As one of the most important downstream products of propylene, polypropylene (PP) plays a key role in industrial production and our daily life.

Beside MAPK signal pathway, NF-κB pathway is the most important downstream signal transduction pathway mediated by LPS [24] [27].

One of the most important downstream effectors in Ca2+ signaling is the calcium/Calmodulin activated serine threonine phosphatase, calcineurin.

Activation of PI3K, which catalyzes inositol lipid phosphorylation to produce phosphatidylinositol-3,4,5-trisphosphate, is one of the most important downstream molecular events following tyrosine kinase receptor activation.

One of the most important downstream proteins affected by mTOR is hypoxia-induced factor 1 α.

Akt, the most important downstream effector of the PI3Ks, is activated by phosphorylation on two residues, T308 and S473.

AGO proteins are sRNA binding and guiding proteins and the most important proteins downstream of the sRNA pathways [ 64].

AKT, p70 S6 kinase, and ribosomal protein S6 are among the most important and representative downstream molecules of these signaling pathways [ 10].

Among the most important molecular events downstream of TKR activation is PI3K activation, which catalyzes the phosphorylation of inositol lipids to phosphatidylinositol-3,4,5-trisphosphate.

Whereas JNK1 was found to be the most important inducer of downstream signaling and JNK2 is an antagonist that competes with JNK1 for ligand binding [ 355], a more activating role of JNK2 in downstream signaling induction has also been described [ 356].

In the same direction, most over-represented networks detected through IPA analysis converged on two hub proteins, MAPK and NFK-B, which are two of the most important kinases activated downstream of the EGF signaling pathway after mitogenic stimulation with EGF (Data not shown).