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Tetrahydrofolate is the most important cofactor in the Wood-Ljungdahl pathway.
As can be seen from Table 4, GCN4 is clearly the most important cofactor for the AAS condition.
NADH was the second most important cofactor while hypoxanthine and N-methylnicotinamide were less involved in the reduction of SR 4233.
In addition to the achievement of the expected operative result, the prevention of complications is the most important cofactor for surgical success.
As Cav-1 directly binds to cholesterol, the most important cofactor in caveolar morphogenesis, we first examined the effect of methyl- β-cyclodextrin (M β-CD, lipid raft disruptor) on caveolar structure to confirm the structural importance of membrane rafts in Cav-1-dependent signaling.
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Fe and Mo are the most important cofactors reported for nitrogenase enzyme activity for H2 production [51].
Trichomonas vaginalis may be emerging as one of the most important cofactors in amplifying HIV transmission, particularly in African-American communities of the United States.
Cohesin is one of the most important cofactors of CTCF, and exhibits distinct functionalities in the presence or absence of CTCF [ 32].
In the case of H2O2 treatment, PHO2 and MSN4 are identified as the most important cofactors for regulation in this condition.
Excess rate ratios for mortality within 1 year of diagnosis showed that stage and age were the most important cofactors, but they also identified the statistically significant effects of sex, income deprivation and geographic area of residence.
However it is important to notice that the above percentages increase to higher values if we consider the fraction of ChIP-seq peaks containing simultaneously ERα and one or more of its most important cofactors, like FoxA1, RARα or AP1 (see the heatmap in Figure 4).
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