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The β-lactam antibiotics, including penicillins, are the most important antimicrobial substances used for mastitis treatment.
In context, one of the most important antimicrobial resistance genes in either strain is aphA1 which confers resistance to neomycin and kanamycin, with neomycin being a drug of choice for the treatment of infection during pig development within Australian pig farms.
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Levels of chlorogenic acid (5- O-caffeoylquinic acid), one of the most important antimicrobials found in cell walls, can be constitutively isolated from resistant cultivars or induced by pathogen infection depending upon the plant species [ 41, 42].
Among the five genes, highly variable pbp2x, pbp1a, and pbp2b are considered most important in antimicrobial resistance [ 26].
Particularly in the outpatient setting, the assumption among healthcare workers that a patient expects an antimicrobial may be the most important driver of antimicrobial over-prescription [ 26].
Mammals are one of the most important sources of antimicrobial peptides (Expósito et al. 2006; Stanford et al. 2009).
β-lactam antibiotics are one, if not the most important group of antimicrobial agents in human and veterinary medicine.
The pathogen is able to counteract the most important mechanisms, namely antimicrobial molecules such as defensins and lysozyme, the complement system, immunoglobulins and phagocytes.
They were found to be the most important QIs for antimicrobial care in adult patients with sepsis.
Methicillin resistant Staphylococcus aureus (MRSA) is the single most important contributor to antimicrobial resistant nosocomial infections [ 4].
B. stearothermophilus is widely used for detection of antibiotics in milk, because it is very sensitive to what is considered the most important group of antimicrobials for this matrix, the β-lactam antibiotics.
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