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Notably most human isolates were characterized from samples collected in the Eastern part of the United States [10], [11], and therefore originate from a relatively small geographic area.
Most human isolates belong to subtype ID, and phylogenetic analyses distinguish two distinct ID genotypes: the Colombia/Venezuela genotype, which is currently circulating in Peru, contrary to previous suggestions (9 ), and the Panama/Peru genotype, which represents most human isolates.
The avian-associated C. dubliniensis isolates investigated belong to MLST clade C1, which includes most human isolates.
Unlike most human isolates in Venezuela, which are distinct from nonhuman strains, oral outbreak isolates are interspersed among nonhuman strains from Venezuela.
In these experiments, the presence of antibodies that neutralized most human isolates of SARS-CoV demonstrated enhanced entry into renal epithelial cells (10).
However, recently the taxonomy of Psychrobacter species has been revised, and most human isolates other than P. phenylpyruvicus belong to the newly characterized species P. faecalis and P. pulmonis (8 ).
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Food-stuffs are mainly contaminated by serogroup 1/2 isolates, whereas most human clinical isolates belong to serotype 4b [ 21, 22], and among these, a small subgroup with unique gene clusters represent the two major epidemic-associated clonal groups [ 23, 24].
CGA isolates were characterized by ACSSuT resistance and represented most human MDR isolates.
The observation includes the fact that HA from most human H2N2 isolates has Leu226 and Ser228 within its RBS, whereas HA from most avian H2 isolates has Gln226 and Gly228.
Most human virus isolates harbor the Q226L substitution responsible for binding to the URT in mammals.
Mice, though largely resistant to infection with most human virus isolates, provide a tractable system for genetic manipulation to study key genes in the regulation of host responses to influenza virus.
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