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Most human diseases originate in animals.
Most human diseases have underlying genetic causes.
This makes the analysis and underlying tools applicable to most human diseases.
Early genetic findings, such as the discovery of the Huntington's disease gene and the cystic fibrosis gene, had led many to believe that most human diseases were caused by a single defective gene.
One reason is complex biological processes of most human diseases which the 'one-drug-one-gene' approach is not effective to treat [4].
Of course, fruit flies don't suffer from most human diseases, but they may be an excellent way to study the genes involved--and possibly find new treatments.
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texts of Galen helped keep medicine in the Dark Ages for centuries with their supremely logical but completely incorrect theories of how derangement of the four humors caused most human disease.
There also has been increasing acceptance of the idea, asserted in 2003 by Khoury, Little, and Burke, that most human disease, if not all, is the result of the interaction between underlying genetic susceptibility and exposures to various components of the environment, including chemical, dietary, infectious, physical, and behavioral factors.
Cancer, much like most human disease, is routinely studied by utilizing model organisms.
Furthermore, most human disease genes and pathways are present in C. elegans (Kaletta and Hengartner, 2006).
In addition, the genetic architecture behind most human disease remains unresolved [ 14– 14].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com