Sentence examples for most human colon from inspiring English sources

Most human colon carcinomas produce IL-8.

SLC5A8 is silenced by methylation in most human colon tumors and reintroduction of this gene leads to growth suppression [ 21].

Carcinoembryonic antigen (CEA) is a well-known and over-expressed TAA in most human colon carcinomas, and vaccination with CEA has been demonstrated to induce, although with only minor effects, both humoral and T-cell responses [ 3].

The elucidation of the effects of Ivermectin discussed above benefited from the fact that most human colon cancer cells tested in vitro in monolayers are TCF-dependent (e.g., van de Wetering et al, 2002; Varnat et al, 2010), thus allowing the in vitro screen.

However, it does not take an active part in the Wnt/β-catenin pathway in colon cancer cells, as mutation of adenomatous polyposis coli (one of the components of Wnt pathway) occurs in most human colon cancers [ 29, 30], thus disconnecting the effector part of the signaling cascade from the Wnt receptors, where DKK1 exerts its inhibitory effect [ 31, 32].

Most human sporadic colon cancers develop gradually as accumulating alterations in gene expression transform normal colonic epithelium to adenocarcinoma.

Most adult human colon crypts appear to be long-lived structures that become mosaic with respect to methylation during aging.

A case in point is the association of mutations of APC with most of human colon tumors [ 16].

COX-2 expression has been found to be upregulated in most human tumors including colon, lung, breast and prostate, which also attributes to cancer-related inflammation, tumor cell proliferation, resistance to apoptosis and angiogenesis [ 43].

Most commonly used human colon carcinoma cell lines express Gb3 probably as a consequence of malignant transformation as Gb3 expression has been linked to cancer (Kovbasnjuk et al., 2005; Engedal et al., 2011).

Compound 12 was found to be the most effective in vitro against human colon adenocarcinoma cell line (LS180).