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The role that microtubules play in mitosis makes them one of the most highly validated targets for the development of chemotherapeutic drugs against rapidly dividing cancer cells [ 5].
The most highly validated gene associated with AD is APP, wherein constitutive gains have previously been linked to AD through familial AD and DS (Prasher et al., 1998; Rovelet-Lecrux et al., 2006; Jonsson et al., 2012; McNaughton et al., 2012).
There are 5,881 sequences (19.5% of the combined dataset) that are experimentally supported by both an assigned MS/MS peptide and a filtered EST alignment, which one might consider to be the most highly validated proteins in the compiled proteome.
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Oncogenic RAS is a highly validated cancer target.
The area has gained momentum by the availability of highly validated chemical tool compound 'probes'probes
This is highly validating, although everyone involved will tell you how early this is.
Despite the well-known problem of comparing measurement devices, target regions of interest (ROI), and reference measurements of different populations, the World Health Organization defines DXA as the method most highly developed technically and most thoroughly validated biologically.
The seven most highly induced putative target genes were also validated by qPCR (Table S5).
Quantitative mass spectrometry (MS) identified nucleosomal histones, which are validated DAMPs, as the most highly enriched proteins released in an actomyosin-dependent manner before secondary necrosis.
ranked biochemically validated CA at 12 months most highly, followed by CA at 6 months, PP at 12 months, and finally PP at 6 months.
We validated the induction of six of the most highly over-expressed genes by qPCR.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com