Sentence examples for most highly downregulated from inspiring English sources

The most highly downregulated gene encodes an uncharacterized protein, with putative Jas- and PHD Zn-finger domains, suggesting that it may be a part of the JA signalling pathway and/or a regulator of development.

For some probes, including the two most highly downregulated ones, no annotated sequence could be identified in the Zv8 release with either strategy, and they were therefore excluded from the subsequent analyses.

The most highly downregulated gene was MME.

The most highly downregulated gene in KO MEFs was the H3f3b gene itself in every case.

The three most highly downregulated genes in our study were MME (0.12 fold), STAT3 (0.13) and DCBLD2 (0.14 fold).

Many cellular functions were affected by furfural, with the most highly downregulated proteins involved in cell wall biosynthesis or sporulation.

Many of the most highly upregulated and downregulated genes have known functions in disc degeneration and extracellular matrix hemostasis.

We particularly focus on the most highly upregulated and downregulated genes identified by the MARS analysis and genes that have been assessed previously in squamate reptiles (table 4).

During the analysis of the 10 most highly upregulated or downregulated transcripts in esl1 Δ esl2 Δ mutants, we noticed a striking association of these genes with neighboring noncoding so-called cryptic unstable transcripts (CUTs) and stable unannotated transcripts (SUTs).

The 10 most highly upregulated or downregulated genes are indicated in Figure 6A, and their genomic contexts are shown in Figure 6, B and C. Upregulated expression was confirmed by semiquantitative reverse-transcription PCR analyses for the transcripts of HXT6 / HXT7 (which are too similar to be distinguishable by reverse-transcription PCR; Figure 6D), PHO89, and HXK1.

The 10 genes most highly upregulated and downregulated in the experimental group are depicted in Figure 2A and 2B, respectively, and the related expression levels are reported in Table 3. Upregulated genes with known roles in disc degeneration included interleukin-6 (Il-6), matrix metallopeptidase 3 (Mmp3), and a disintegrin and metalloproteinase with thrombospondin motifs 5 (Adamts5).