Your English writing platform
Discover LudwigSuggestions(5)
Exact(7)
It holds much more generally, even for the most highly constrained pairs.
Table 1 shows the 15 most highly constrained reaction sets, that is, those sets with the smallest P-value.
The figure shows that the fraction of genomes encoding only one reaction is greater than 20percentt except for the most highly constrained reaction pairs.
In contrast, GO biological process terms related to functions in translation, protein localization, and chromatin structure were overrepresented for the most highly constrained genes (table 5).
I asked how important gene linkage is in constraining reaction evolution by examining the most highly constrained reaction pairs and how closely together their encoding genes are linked in a genome.
Noteworthy is that several cofactor biosyntheses appear among the most highly constrained reaction sets They include the synthesis pathways of cobalamin (vitamin B12); biotin (vitamin H or B7), a cofactor in fatty acid and leucine biosynthesis, and pyrroloquinoline quinone (PQQ), a redox cofactor.
Similar(53)
As donor representatives fly back home to their capitals, most will encounter either highly constrained or skeptical audiences.
Most informational genes are highly constrained by interactions with other proteins and evolve slowly (Rivera et al. 1998), which can potentially lead to slower divergence of nucleotide usage patterns.
Additionally, most of WFLO problems are highly constrained, where many unfeasible zones can exist inside the proposed wind farm boundaries, which in turn complicates the optimization process.
Thus, either the lamprey lineage diverged from jawed vertebrates before most gnathostome CNE sequences became highly constrained or these CNEs have evolved much more rapidly in the lamprey genome than in jawed vertebrate genomes.
Despite the successful development of effective medications to treat health conditions such as malaria, diarrheal disease, HIV and tuberculosis, access to these medications remains highly constrained in most developing countries [ 1].
More suggestions(15)
most highly coordinated
most highly developed
most highly upregulated
most highly detected
most highly prized
most highly trained
most highly anticipated
most highly stressed
most highly paid
most highly qualified
most highly represented
most highly valued
most highly enriched
most highly associated
most highly refined
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com